Procaine penicillin G 300,000i.u./mL in a sterile aqueous suspension for injection.
 
Action:
Procaine penicillin is a moderately soluble drug that provides therapeutic effects from a single injection for about 24 hours. Penicillin inhibits cell wall synthesis in susceptible bacteria.
 
Indication:
Treatment of respiratory, urogenital, gastro-intestinal, musculoskeletal and soft tissue infections caused by penicillin G procaine sensitive aerobic and anaerobic Gram-positive bacteria and some Gram-negative bacteria in cattle, pigs, sheep, horses, cats and dogs, and in clinical mastitis in cattle and sheep.
 
Cattle: For the treatment of bacterial respiratory disease (P. multocida, M. haemolytica, H. somni), foot rot (F. necrophorum), urogenital infections (T. pyogenes, F. necrophorum), clostridial infections (Clostridium difficile), and clinical mastitis caused by Streptococcus spp. and penicillin G-sensitive Staphylococcus aureus.
 
Sheep: For the treatment of bacterial respiratory disease (P. haemolytica, P. multocida), footrot and foot scald (F. necrophorum), necrotic laryngitis (F. necrophorum), urogenital infections (C. renale, C. perfringens type C & D), Erysipelothrix polyarthritis (E. rhusiopathiae), omphalophlebitis (T. pyogenes), Listeriosis (L. monocytogenes), and clinical mastitis caused by Streptococcus spp. and penicillin G-sensitive Staphylococcus aureus.
 
Pigs: For the treatment of bacterial respiratory disease (A. pleuropneumoniae, B. bronchiseptica, T. pyogenes), necrotic enteritis (C. perfringens), Glässer’s disease (H. parasuis), meningitis (S. suis), and Erysipelas (E. rhusiopathiae).
 
Horses: For the treatment of bacterial pneumonia (S. equi subsp. zooepidemicus, Staphylococcus spp., Actinobacillus spp.), for lung abscesses (Streptococcus spp., Actinobacillus spp.), pleuropneumonia (S. equi subsp. zooepidemicus, Staphylococcus spp., Actinobacillus spp.), and strangles (Streptococcus equi subsp. equi).
 
Dogs and Cats: For the treatment of bacterial respiratory, thoracic, skin- and wound infections (Staphylococcus spp., Streptococcus spp., Pasteurella spp.), Leptospirosis (Leptospira spp.), and pyelonephritis and urogenital infections (Staphylococcus spp.)
 
Warning:
Do not administer to an animal previously found to be hypersensitive to penicillins, cephalosporins, procainum or one of the excipients. Do not inject intravenously. Hypersensitivity reactions, such as urticaria, contact dermatitis and anaphylaxis may very rarely occur
 
DOSAGE:
SHAKE WELL BEFORE USE.
In food producing animals, injection must be given into the anterior half of the neck.
Larger doses must be divided - do not inject more than 20 mL at one site.
Administer the selected dose daily for 3 to 5 days.

Dogs, cats: 30,000 I.U./kg b.w. or 1 mL/10 kg b.w., every 24 hours by intramuscular or subcutaneous injection.
 
Cattle, sheep, pigs, horses: 18,000 I.U./kg b.w. or 0.6 mL/10 kg b.w., every 24 hours by intramuscular injection.
 
 
Withholding Times:
It is an offence for users of this product to cause residues exceeding the relevant MRL in the Food Notice: Maximum Residue Levels for Agricultural Compounds.
 
MILK:
Cattle: After three, four or five doses, milk intended for human consumption must be discarded during treatment and for not less than 8 milkings or approximately 96 hours following the last treatment.
Sheep: Milk intended for sale for human consumption must be discarded during treatment and for 14 days following the last injection.
 
MEAT:
Cattle sheep & pigs producing meat and offal for human consumption must not be sold for slaughter either during treatment or within 7 days of the last treatment.
Horses producing meat and offal for human consumption must not be sold for slaughter either during treatment or within 63 days of the last treatment.
Bobby calves: Not for use in bobby calves. Milk from treated cows should not be fed to bobby calves during the treatment or within the withholding period.
 
Other Information:
The product has a shelf-life of 48 months (glass vials) / 36 months (PET vials) when stored at 2-8°C in a refrigerator or 3 months when stored below 25°C.
Shelf-life after first opening: 28 days when stored below 25°C.
Safety Data Sheet available upon request
 
Penicillin G procaine is an antibiotic in the beta-lactam family and is considered highly important to human and animal health. The use of this antibiotic should only be for the minimum period needed to meet the clinical objective. Clinical response to this antibiotic should be monitored during treatment, and choice of therapy reviewed if clinical signs of disease persist, increase, or relapse. In the event of treatment failure, culture and sensitivity should be considered to determine an appropriate alternative therapy. Indiscriminate use of this antibiotic can contribute to the development of antibiotic resistance.
 
Available only under veterinary authorisation.